RESEARCH

The expertise of the MicroFlow Cell is focused on the following research lines:

• Single IMage PArasite Quantification in stool (SIMPAQ),
• engineering and production of microparticles,
• microdevices for advanced separations,
• biosensors,
• organ-on-chip,
• microbial cell factories,
• mycelium matreials.
   

Research is performed by a dedicated team of experts and technicians with access to microfluidics lab and workshop, cleanroom facilities equipped for advanced micro- and nanofabrication (core facility MICROLAB), microbiology lab (BSL-2), OpenBioLab Brussels, diabetes lab, animal testing (core facility ANIM).

Rail configuration for lateral particle transport across intact co-flows: effect of wall and rail geometry on liquid and particle transport

Ziemecka, I.,  de Hemptinne, A.,  Misko, V.R,  Briet, M., Gelin, P., ; Maes, D.,  De Malsche, W., Soft matter (2023)

Application of generalized dispersion theory to vortex chromatography 

Westerbeek, E.Y, Gelin, P., Frankel, I., Olthuis, W., Eijkel, J.C.T., De Malsche, W., J. Chromatogr. A (2022), 462970

On the potential use of two-photon polymerization to 3D print chromatographic packed bed supports

Matheuse, F.  Vanmol, K, Van Erps, J.,  De Malsche, W.,  Ottevaere, H., Desmet, G., J. Chromatogr. A (2022), 1663

The Effect of Controlled Mixing on ROY Polymorphism

Van Nerom, M.,  Gelin, P.  Hashemiesfahan, M De Malsche, W, ; Lutsko, J.F.,  Maes, D.,  Galand, Q., Crystals (2022), 12, 577

Concepts and recent advances in microchip electrophoresis coupled to mass spectrometry: Technologies and applications

Naghdi, E.,  Moran, G.E.,  Reinau, M.E.,  De Malsche, W.,  Neususs, C., Electrophoresis  (2022)

Influence of Centrifugation and Shaking on the Self-Assembly of Lysozyme Fibrils

Krzek, M., Stroobants, S., Gelin, P., De Malsche, W., Maes, D., Biomolecules (2022), 12, 1746

Rail induced lateral migration of particles across intact co-flowing liquids

Ziemecka, I., de Hemptinne, A., Misko, V., Briet, M., Gelin, P. P., Bihi, I., Maes, D., & De Malsche, W.,  Scientific Reports – Nature (2022), 12, [21775]

Reducing Taylor-Aris dispersion by exploiting lateral convection associated with acoustic streaming

Gelin, P., Maes, D., De Malsche, W., Chemical Engineering Journal (2021), 128031

Overloading behavior of fenoprofen and naproxen as two model compounds on a non-porous silicon pillar array column

Naghdi, E., De Malsche, W., Journal of Chromatography A (2021), 1651, 462332

Inducing AC-electroosmotic flow using electric field manipulation with insulators

Tiflidis, C., Westerbeek, E., Jorissen, K., Olthuis, W., Eijkel, ,J., De Malsche, W., Lab-on-a-chip (2021), 21, 3105-3111

Migration Behavior of Low-Density Particles in Lab-on-a-Disc Devices: Effect of Walls

Misko, V.R., Kryj, A., Tamandjo Ngansop, A.-M., Yazdani, S., Briet, M., Basinda, N., Mazigo, H.D., De Malsche, W., Micromachines (2021), 12(9), 1032

Fabrication, Boron Leaching, and Electrochemical Impedance Spectroscopy of Nanoporous P-Type Silicon

Mebed, A.M.,  De Malsche, W. , Abd-Elnaiem, A.M., Silicon (2021),  1876-990X

Reduction of Taylor-Aris dispersion by lateral mixing for chromatography applications

Westerbeek, E., Bomer, J.G., Olthuis, W., Eijkel, J.E., De Malsche, W., Lab-on-a-chip (2020), 20, 3938 – 3947

Performance of laterally elongated pillar array columns in capillary electrochromatography mode

Baca, M., Kryj, A., Naghdi, E., Gelin, P., Sukas, S., Laha, P., Terryn, H., Ottevaere, O., De Malsche, W.,  Electrophoresis (2020), 41, 1287-1295

Microfluidic device for high throughput production of monodisperse droplets

Gelin, P., Bihi, I., Ziemecka, I. Thienpont, B., Christiaens, J., Hellemans, K., Maes, D., De Malsche, W., Industrial & Engineering Chemistry Research (2020), 59, 12784–12791

Anisotropic Exclusion Effect between Photocatalytic Ag/AgCl Janus Particles and Passive Beads in a Dense Colloidal Matrix

Huang, T., Gobeil, S., Wang, X., Misko, V., Nori, F., De Malsche, W., Fassbender, J., Makarov, D., Cuniberti, G. & Baraban, L., 30 Jun 2020, In : Langmuir. 36, 25, p. 7091-7099 9 p.

Influence of Anodizing Parameters on the Electrochemical Characteristics and Morphology of Highly Doped P-type Porous Silicon

Mebed, A. M., Abd-Elnaiem, A. M. & De Malsche, W., 9 May 2020, In : SILICON.

Simultaneous enantioseparation of nonsteroidal anti-inflammatory drugs by a one-dimensional liquid chromatography technique using a dynamically coated chiral porous silicon pillar array column

Naghdi, E., Fakhari, A. R., Baca, M. & De Malsche, W., 29 Mar 2020, In : Journal of Chromatography A. 1615, 460752.

Influence of Shear on Protein Crystallization under Constant Shear Conditions

Stroobants, S., Callewaert, M., Krzek, M., Chinnu, S., Gelin, P., Ziemecka, I., Lutsko, J. F., De Malsche, W. & Maes, D., 4 Mar 2020, In : Crystal Growth and Design. 20, 3, p. 1876-1883 8 p.

Microfluidic Device for High-Throughput Production of Monodisperse Droplets

Gelin, P. P., Bihi, I., Ziemecka, I., Thienpont, B., Christiaens, J. W., Hellemans, K. H., Maes, D. & De Malsche, W., 2 Mar 2020, In : Industrial & Engineering Chemistry Research. 2020, p. 1-7 7 p., ie-2019-05935r.R2.

Development of a Lab-on-a-Disk Platform with Digital Imaging for Identification and Counting of Parasite Eggs in Human and Animal Stool

Sukas, S., Van Dorst, B., Kryj, A., Lagatie, O., De Malsche, W. & Stuyver, L. J., 5 Dec 2019, In : Micromachines (Basel). 10, 12, 852.

Achieving a Peak Capacity of 1800 Using an 8 m Long Pillar Array Column

Baca, M., Desmet, G., Ottevaere, P. D. I. H. & De Malsche, W., 3 Sep 2019, In : Analytical Chemistry. 91, 17, p. 10932-10936 5 p.

Decreased Peak Tailing during Transport of Solutes in Porous Media with Alternate Adsorption Properties

Rana, C., De Malsche, W. & De Wit, A., 10 Aug 2019, In : Chemical Engineering Science. 203, p. 415-424 9 p.

Study on the Mixing and Migration Behavior of Micron-size Particles in Acoustofluidics

Gelin, P. P., Sardan Sukas, Ö., Hellemans, K., Maes, D. & De Malsche, W., 1 Aug 2019, In : Chemical Engineering Journal. 369, p. 370-375 6 p.

Focusing of Microcrystals and Liquid Condensates in Acoustofluidics

Gelin, P. P., Van Lindt, J., Bratek-Skicki, A., Ziemecka, I., Stroobants, S., Krzek, M., Tompa, P., De Malsche, W. & Maes, D., 26 Feb 2019, In : Crystals. 9, 3, 9 p., 120.

Glucocorticoids and Checkpoint Tyrosine Kinase Inhibitors Stimulate Rat Pancreatic Beta Cell Proliferation Differentiall

Akbib, S., Stichelmans, J., Stangé, G., Ling, Z., Assefa, Z. & Hellemans, K. H., 19 Feb 2019, In : PLoS ONE. 14, 2, 20 p., e0212210.